RPL8

Across TCGA patient cohorts, RPL8 protein abundance is significantly associated with the RNA expression of many other genes, with 12,392 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL8-associated genes across cancer lineages are SEPTIN7P14, PPM1A, and ANKRD12. Each is linked with RPL8 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPL8-to-partner and partner-to-RPL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL8 versus SEPTIN7P14 in HNSC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL8→partner) and Y-score (partner→RPL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN7P14 →	-0.514	-0.299	.007	.006	3	5
GBM	PPM1A →	-0.519	-0.345	<.001	<.001	3	4
BRCA	ANKRD12 →	-0.705	-0.465	<.001	<.001	3	4
BRCA	GAB1 →	-0.670	-0.308	<.001	<.001	3	4
HNSC	CRBN →	-0.585	-0.287	<.001	.001	3	4
HNSC	RNF146 →	-0.455	-0.287	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,392 associations by consensus.

RPL8 vs SEPTIN7P14 — HNSC

Explore this scatter interactively →