RPL8

Across TCGA patient cohorts, RPL8 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL8-associated genes across cancer lineages are Ku80 and c-Met_pY1235. Each is linked with RPL8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL8-to-partner and partner-to-RPL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by RPL8-low versus RPL8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL8→partner) and Y-score (partner→RPL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.488	+2.820	<.001	.036	3	1
UCEC	c-Met_pY1235 →	+0.112	+2.817	.014	.036	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Ku80 by RPL8 expression — UCEC

Explore this box plot interactively →