RPL8

Across TCGA cell cohorts, RPL8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,267 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPL8-associated GO terms across cancer lineages are Central nervous system morphogenesis, U4 snRNA 3'-end processing, and Macroautophagy. Each is linked with RPL8 in more than 13 cancer types. Because this analysis shows association rather than direction, both RPL8-to-partner and partner-to-RPL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Central nervous system morphogenesis grouped by RPL8-low versus RPL8-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL8→partner) and Y-score (partner→RPL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Central nervous system morphogenesis →	-0.416	-0.394	<.001	.001	3	14
URINARY_TRACT	U4 snRNA 3'-end processing →	+0.159	+1.065	<.001	<.001	3	12
BLOOD_Myeloma	Macroautophagy →	-0.064	-0.981	<.001	.001	3	11
LUNG_NSCLC_LUSC	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.161	+1.228	.002	<.001	3	10
BLOOD_Myeloma	Process utilizing autophagic mechanism →	-0.050	-1.008	<.001	<.001	3	9
BLOOD_Myeloma	Autophagy →	-0.050	-1.008	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,267 associations by consensus.

Central nervous system morphogenesis by RPL8 expression — BLOOD_Leukemia

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