Across TCGA pan-cancer cohorts, RPL7P54 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL7P54’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL7P54 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL7P54 is over-expressed in tumor.
HNSC and THCA are the cancer types where RPL7P54 tumor–normal differential expression is most reproducible.