RPL7P53

Across TCGA pan-cancer cohorts, RPL7P53 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPL7P53 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPL7P53 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL7P53 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, CHOL, and BLCA are the cancer types where RPL7P53 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.630	0.286	.001	111	view →
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
BLCA	DFS	Tertile	IV	0.214	0.493	.008	45	view →
PAAD	OS	Tertile	All	0.321	0.663	.001	42	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	36	view →
BRCA	DFS	Tertile	All	0.467	0.535	.020	30	view →
LUAD	DFS	Tertile	All	0.813	0.642	.003	30	view →
PCPG	OS	Tertile	All	0.822	0.980	<.001	27	view →
THCA	DFS	Tertile	IV	0.243	0.801	.021	21	view →
ESCA	DFS	Quartile	III,IV	0.574	0.328	.015	18	view →
LGG	OS	Tertile	All	0.974	0.881	.017	15	view →
STAD	DFS	Tertile	III,IV	0.475	0.629	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RPL7P53–HNSC (DFS)

Open the HNSC breakdown →