RPL7P49

Across TCGA pan-cancer cohorts, RPL7P49 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL7P49’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL7P49 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL7P49 is over-expressed in tumor, although a few such as PAAD and COAD show the opposite, repressed pattern.

HNSC, PAAD, and BLCA are the cancer types where RPL7P49 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7P49 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.045	.002	8	view →
PAAD	Male	All	−0.135	.012	4	view →
BLCA	Female	All	+0.128	.022	4	view →
BRCA	All	All	+0.098	.034	3	view →
LUAD	All	All	+0.195	.016	2	view →
STAD	Male	IV	+0.249	.027	1	view →
COAD	Male	IV	−0.062	.046	1	view →
THCA	Male	All	−0.045	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL7P49–HNSC

Open the HNSC breakdown →