RPL7P46

Across TCGA pan-cancer cohorts, RPL7P46 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPL7P46’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL7P46 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL7P46 is over-expressed in tumor.

THCA, BLCA, and KIRP are the cancer types where RPL7P46 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7P46 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	+0.135	.011	5	view →
BLCA	Male	III,IV	+0.141	.031	3	view →
KIRP	Female	II,III,IV	+0.196	.002	2	view →
PAAD	Male	All	+0.165	.022	2	view →
BRCA	All	All	+0.109	.042	2	view →
LUAD	All	All	+0.169	.044	1	view →
KICH	Female	III,IV	+0.086	.022	1	view →
HNSC	All	III,IV	+0.048	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPL7P46–THCA

Open the THCA breakdown →