RPL7P21

Across TCGA pan-cancer cohorts, RPL7P21 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL7P21’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RPL7P21 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL7P21 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, STAD, and KIRP are the cancer types where RPL7P21 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7P21 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.124	.018	3	view →
STAD	Male	II,III,IV	+0.277	.036	2	view →
KIRP	Female	II,III,IV	+0.250	.045	2	view →
LUAD	All	All	+0.288	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPL7P21–THCA

Open the THCA breakdown →