Across TCGA pan-cancer cohorts, RPL7P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPL7P1’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RPL7P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL7P1 is over-expressed in tumor, although a few such as BRCA and BLCA show the opposite, repressed pattern.
LIHC, KIRC, and BRCA are the cancer types where RPL7P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.