RPL7L1P12

Across TCGA pan-cancer cohorts, RPL7L1P12 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL7L1P12’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RPL7L1P12 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL7L1P12 is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where RPL7L1P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7L1P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.113	.007	4	view →
BRCA	All	III,IV	−0.098	.012	2	view →
LUAD	Female	II,III,IV	−0.139	.005	1	view →
THCA	Male	All	+0.041	.031	1	view →
KICH	All	All	−0.036	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPL7L1P12–LUSC

Open the LUSC breakdown →