RPL7L1

Across TCGA patient cohorts, RPL7L1 mutation is significantly associated with the RNA expression of many other genes, with 557 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL7L1-associated genes across cancer lineages are MIR5696, IGHD3-16, and MIR4796. Each is linked with RPL7L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL7L1-to-partner and partner-to-RPL7L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5696 grouped by RPL7L1-low versus RPL7L1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL7L1→partner) and Y-score (partner→RPL7L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR5696 →	+0.545	+5.269	<.001	.001	3	2
UCEC	IGHD3-16 →	+1.840	+3.680	<.001	<.001	3	2
BLCA	MIR4796 →	+0.464	+6.018	<.001	.002	3	2
SKCM	RNA5SP491 →	+0.439	+4.265	<.001	.003	3	2
COAD	RNU6-521P →	+0.782	+7.741	<.001	.009	3	2
BLCA	NDUFS5P1 →	+0.224	+5.038	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

MIR5696 by RPL7L1 expression — CESC

Explore this box plot interactively →