RPL7L1

Across TCGA cell cohorts, RPL7L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,285 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPL7L1-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, DNA-templated DNA replication, and DNA-templated transcription initiation. Each is linked with RPL7L1 in more than 14 cancer types. Because this analysis shows association rather than direction, both RPL7L1-to-partner and partner-to-RPL7L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by RPL7L1-low versus RPL7L1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL7L1→partner) and Y-score (partner→RPL7L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of RNA export from nucleus →	+0.169	+0.941	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.131	+0.811	.001	.007	3	14
URINARY_TRACT	DNA-templated transcription initiation →	+0.060	+0.785	<.001	<.001	3	14
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.113	+0.693	<.001	<.001	2	15
OVARY	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.090	+0.649	<.001	<.001	3	14
OVARY	Transcription initiation at RNA polymerase I promoter →	+0.088	+0.644	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,285 associations by consensus.

Negative regulation of RNA export from nucleus by RPL7L1 expression — PANCREAS

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