RPL7AP69

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL7AP69 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL7AP69’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL7AP69 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL7AP69 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC and THCA are the cancer types where RPL7AP69 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7AP69 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll+0.008.0233view →
THCAAllII,III,IV−0.019.0461view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RPL7AP69–KIRC

Tumor-vs-normal expression box plot for RPL7AP69 RNA in KIRC.

Open the KIRC breakdown →

Exploration