RPL7AP49

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL7AP49 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL7AP49’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RPL7AP49 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL7AP49 is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.

BRCA and PRAD are the cancer types where RPL7AP49 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL7AP49 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAFemaleAll−0.068.0044view →
PRADAllAll−0.055.0392view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration