RPL7AP2

Across TCGA pan-cancer cohorts, RPL7AP2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RPL7AP2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RPL7AP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL7AP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

THCA, KIRC, and HNSC are the cancer types where RPL7AP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	IV	0.577	0.939	.006	26	view →
KIRC	DFS	Tertile	All	0.606	0.739	.017	22	view →
HNSC	OS	Median	IV	0.488	0.278	.006	22	view →
OV	OS	Quartile	III,IV	0.597	0.717	.012	18	view →
ACC	DFS	Quartile	All	0.451	0.844	.023	9	view →
PCPG	OS	Median	All	0.939	1.000	.025	9	view →
UVM	DFS	Quartile	III,IV	0.290	0.633	.031	7	view →
LGG	OS	Tertile	All	0.836	0.699	.015	6	view →
LUSC	OS	Tertile	II,III,IV	0.433	0.281	.013	5	view →
LAML	DFS	Quartile	All	0.544	0.295	.031	4	view →
READ	DFS	Quartile	III,IV	0.329	0.680	.011	4	view →
KIRP	DFS	Tertile	III,IV	0.258	0.607	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RPL7AP2–THCA (OS)

Open the THCA breakdown →