RPL7

Across TCGA patient cohorts, RPL7 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL7-associated genes across cancer lineages are CMP, Mast cells, and Mesangial cells. Each is linked with RPL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL7-to-partner and partner-to-RPL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by RPL7-low versus RPL7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL7→partner) and Y-score (partner→RPL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CMP →	+0.038	+2.180	.016	.036	2	2
UCEC	Mast cells →	+0.027	+2.212	<.001	.034	3	1
UCEC	Mesangial cells →	-0.044	-3.311	.028	.010	3	1
UCEC	Myocytes →	+0.046	+2.212	.006	.034	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CMP by RPL7 expression — UCEC

Explore this box plot interactively →