RPL6P5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL6P5 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPL6P5 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RPL6P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL6P5 expression acts as an unfavorable survival marker, although some lineages such as MESO and UCEC show a favorable association.

BRCA, BLCA, and COAD are the cancer types where RPL6P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.9080.965<.00178view →
BLCAOSTertileIII,IV0.4770.701.00554view →
COADOSTertileII,III,IV0.6910.868<.00145view →
CESCDFSTertileAll0.6640.827.02836view →
THCAOSTertileAll0.9700.994.00436view →
MESOOSTertileIV0.8950.419.00731view →
READOSTertileIII,IV0.1110.890<.00127view →
ACCOSTertileAll0.1520.705.00421view →
LIHCOSTertileAll0.5880.808<.00121view →
THYMOSTertileII,III,IV0.7160.954.00814view →
OVDFSTertileIII,IV0.2730.380.03512view →
STADDFSTertileIV0.1600.402.0449view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration