Across TCGA pan-cancer cohorts, RPL6P29 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPL6P29’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RPL6P29 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL6P29 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
PAAD, THCA, and CHOL are the cancer types where RPL6P29 tumor–normal differential expression is most reproducible.