RPL6

Across TCGA cell cohorts, RPL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,544 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL6-associated GO terms across cancer lineages are Regulation of pattern recognition receptor signaling pathway, Glial cell migration, and tRNA 5'-end processing. Each is linked with RPL6 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPL6-to-partner and partner-to-RPL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of pattern recognition receptor signaling pathway grouped by RPL6-low versus RPL6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL6→partner) and Y-score (partner→RPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	-0.074	-1.068	<.001	<.001	3	13
LIVER	Glial cell migration →	-0.219	-0.667	.006	.009	3	13
OVARY	tRNA 5'-end processing →	+0.098	+0.586	.002	.005	3	13
SOFT_TISSUE	Mitochondrial transcription →	+0.098	+0.717	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	-0.092	-1.164	<.001	<.001	3	12
BONE	Viral process →	-0.088	-0.689	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,544 associations by consensus.

Regulation of pattern recognition receptor signaling pathway by RPL6 expression — UPPER_AERODIGESTIVE_TRACT

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