RPL6

Across TCGA cell cohorts, RPL6 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPL6-associated genes across cancer lineages are OR1L6, QRFPR, and OR2J2. Each is linked with RPL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL6-to-partner and partner-to-RPL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by RPL6-low versus RPL6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL6→partner) and Y-score (partner→RPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR1L6 →	+0.022	+4.437	<.001	.004	3	1
LARGE_INTESTINE	QRFPR →	+0.713	+3.854	.007	.006	3	1
LARGE_INTESTINE	OR2J2 →	+0.019	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR1L6 by RPL6 expression — LARGE_INTESTINE

Explore this box plot interactively →