RPL6

Across TCGA cell cohorts, RPL6 mutation is significantly associated with the mutation status of many other genes, with 2,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPL6-associated genes across cancer lineages are BRIP1, PCDHA2, and ZFP64. Each is linked with RPL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPL6-to-partner and partner-to-RPL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRIP1 grouped by RPL6-low versus RPL6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL6→partner) and Y-score (partner→RPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BRIP1 →	+3.157	+4.665	.003	.003	1	3
BLOOD_Leukemia	PCDHA2 →	+3.479	+4.932	.002	.002	1	3
LARGE_INTESTINE	ZFP64 →	+1.693	+3.506	.008	.008	1	3
LARGE_INTESTINE	CC2D2A →	+2.080	+3.906	.003	.003	1	3
LARGE_INTESTINE	ANKS1A →	+3.137	+3.807	.001	.001	1	3
LARGE_INTESTINE	UBE3C →	+2.459	+3.321	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,031 associations by consensus.

BRIP1 by RPL6 expression — BLOOD_Leukemia

Explore this box plot interactively →