Across TCGA pan-cancer cohorts, RPL5P8 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL5P8’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPL5P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P8 is over-expressed in tumor, although a few such as KIRP and BLCA show the opposite, repressed pattern.

COAD, KIRP, and KIRC are the cancer types where RPL5P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.278	.001	5	view →
KIRP	Female	All	−0.088	<.001	3	view →
KIRC	Female	All	+0.079	.036	3	view →
BLCA	Female	IV	−0.256	.025	1	view →
LUAD	Male	All	+0.144	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RPL5P8 RNA expression & survival · all RPL5P8 data types