RPL5P35

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL5P35 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL5P35 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RPL5P35 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL5P35 expression acts as an unfavorable survival marker, although some lineages such as THCA and LAML show a favorable association.

OV, STAD, and THCA are the cancer types where RPL5P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSMedianAll0.2570.368.00158view →
STADDFSQuartileAll0.5220.802.00534view →
THCADFSMedianAll0.9360.860.00218view →
LAMLDFSTertileAll0.5130.258.01518view →
MESODFSTertileIII,IV0.7160.154.00612view →
LIHCOSTertileIII,IV0.1770.417.0169view →
ESCAOSTertileII,III,IV0.5830.414.0279view →
LUADOSQuartileII,III,IV0.6260.782.0149view →
PRADOSTertileAll1.0000.833.0178view →
SKCMOSMedianIV0.1840.582.0327view →
UCECOSTertileII,III,IV0.7820.892.0236view →
ACCOSTertileII,III,IV0.5990.822.0354view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration