Across TCGA pan-cancer cohorts, RPL5P20 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPL5P20’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where RPL5P20 RNA is repressed in tumor relative to normal tissue. In most cancer types RPL5P20 is over-expressed in tumor, although a few such as ESCA and KIRP show the opposite, repressed pattern.

ESCA, LUSC, and KIRC are the cancer types where RPL5P20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Female	All	−0.176	.039	1	view →
LUSC	Female	III,IV	+0.110	.008	1	view →
KIRC	Male	All	+0.023	.010	1	view →
KIRP	Male	All	−0.012	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RPL5P20 RNA expression & survival · all RPL5P20 data types