Across TCGA pan-cancer cohorts, RPL5P13 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL5P13’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RPL5P13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P13 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
BLCA, BRCA, and STAD are the cancer types where RPL5P13 tumor–normal differential expression is most reproducible.