RPL5P11

Across TCGA pan-cancer cohorts, RPL5P11 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RPL5P11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPL5P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL5P11 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

KIRC, LIHC, and UCEC are the cancer types where RPL5P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL5P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.100	<.001	8	view →
LIHC	Female	II,III,IV	+0.080	.007	5	view →
UCEC	All	All	−0.196	.005	4	view →
BRCA	All	III,IV	−0.121	.017	2	view →
COAD	All	All	+0.121	.024	2	view →
PRAD	All	All	+0.110	.034	2	view →
THCA	All	All	−0.066	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RPL5P11–KIRC

Open the KIRC breakdown →