RPL5P1

Across TCGA pan-cancer cohorts, RPL5P1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RPL5P1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RPL5P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL5P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

LIHC, ACC, and KIRP are the cancer types where RPL5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.432	0.657	<.001	85	view →
ACC	DFS	Median	II,III,IV	0.337	0.693	<.001	65	view →
KIRP	DFS	Tertile	All	0.820	0.966	<.001	37	view →
SKCM	OS	Median	III,IV	0.779	0.620	.001	35	view →
CESC	OS	Tertile	II,III,IV	0.846	0.607	.013	30	view →
STAD	DFS	Tertile	All	0.215	0.395	.009	25	view →
LUSC	OS	Tertile	All	0.730	0.591	.009	24	view →
THCA	DFS	Median	All	0.908	0.772	.002	24	view →
SARC	OS	Tertile	All	0.649	0.836	<.001	22	view →
OV	OS	Tertile	III,IV	0.302	0.406	.013	20	view →
MESO	DFS	Quartile	All	0.765	0.141	.006	18	view →
COAD	OS	Median	All	0.885	0.727	.003	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RPL5P1–LIHC (OS)

Open the LIHC breakdown →