RPL5

Across TCGA patient cohorts, RPL5 protein abundance is significantly associated with the RNA expression of many other genes, with 25,372 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPL5-associated genes across cancer lineages are JAM2, GPIHBP1, and SEPTIN4. Each is linked with RPL5 in more than 8 cancer types. Because this analysis shows association rather than direction, both RPL5-to-partner and partner-to-RPL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL5 versus JAM2 in HNSC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL5→partner) and Y-score (partner→RPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	JAM2 →	-0.870	-0.221	<.001	<.001	3	9
CCRCC	GPIHBP1 →	-1.558	-0.262	<.001	<.001	3	9
GBM	SEPTIN4 →	-0.746	-0.225	<.001	<.001	3	9
CCRCC	CNRIP1 →	-0.907	-0.263	<.001	<.001	3	9
COAD	PRELP →	-1.615	-0.233	<.001	<.001	3	9
BRCA	APOD →	-1.717	-0.177	.006	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,372 associations by consensus.

RPL5 vs JAM2 — HNSC

Explore this scatter interactively →