RPL5

Across TCGA patient cohorts, RPL5 mutation is significantly associated with the RNA expression of many other genes, with 1,702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL5-associated genes across cancer lineages are MIR6075, MIR548D2, and LINC01072. Each is linked with RPL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL5-to-partner and partner-to-RPL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6075 grouped by RPL5-low versus RPL5-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL5→partner) and Y-score (partner→RPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR6075 →	+0.529	+5.544	<.001	.004	3	2
BRCA	MIR548D2 →	+0.247	+4.950	<.001	.003	3	2
CESC	LINC01072 →	+0.198	+5.345	<.001	.001	3	2
LIHC	RNU6-167P →	+0.381	+5.033	<.001	.009	3	2
UCEC	LSM10 →	+0.403	+2.321	<.001	<.001	3	2
UCEC	ASB12 →	-0.757	-2.376	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,702 associations by consensus.

MIR6075 by RPL5 expression — LIHC

Explore this box plot interactively →