RPL5

Across TCGA cell cohorts, RPL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPL5-associated GO terms across cancer lineages are Macroautophagy, Process utilizing autophagic mechanism, and Autophagy. Each is linked with RPL5 in more than 12 cancer types. Because this analysis shows association rather than direction, both RPL5-to-partner and partner-to-RPL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by RPL5-low versus RPL5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL5→partner) and Y-score (partner→RPL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Macroautophagy →	-0.045	-0.971	.001	.001	3	13
PANCREAS	Process utilizing autophagic mechanism →	-0.055	-0.773	.005	<.001	2	13
PANCREAS	Autophagy →	-0.055	-0.773	.005	<.001	2	13
SKIN	Lytic vacuole organization →	-0.058	-0.609	<.001	<.001	3	12
SKIN	Lysosome organization →	-0.058	-0.609	<.001	<.001	3	12
PANCREAS	Multi-pass transmembrane protein insertion into ER membrane →	-0.116	-0.522	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Macroautophagy by RPL5 expression — BREAST

Explore this box plot interactively →