Across TCGA pan-cancer cohorts, RPL4P7 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL4P7’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPL4P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL4P7 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.
COAD, HNSC, and KIRC are the cancer types where RPL4P7 tumor–normal differential expression is most reproducible.