Across TCGA pan-cancer cohorts, RPL41 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RPL41 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPL41 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPL41 expression acts as an unfavorable survival marker.

UCEC and BLCA are the cancer types where RPL41 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →
BLCA	DFS	Median	All	0.015	0.594	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RPL41 tumor-vs-normal RNA expression · all RPL41 data types