RPL4

Across TCGA patient cohorts, RPL4 protein abundance is significantly associated with the RNA expression of many other genes, with 17,557 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPL4-associated genes across cancer lineages are KLF2, N4BP2L1, and DIXDC1. Each is linked with RPL4 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPL4-to-partner and partner-to-RPL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPL4 versus KLF2 in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL4→partner) and Y-score (partner→RPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KLF2 →	-1.129	-0.391	.001	<.001	3	7
HNSC	N4BP2L1 →	-0.652	-0.171	<.001	<.001	3	7
BRCA	DIXDC1 →	-0.710	-0.277	<.001	<.001	3	7
BRCA	COLEC12 →	-1.190	-0.309	<.001	<.001	3	7
HNSC	SAP30L →	-0.662	-0.229	<.001	<.001	3	7
LUAD	SHE →	-0.836	-0.230	.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,557 associations by consensus.

RPL4 vs KLF2 — OV

Explore this scatter interactively →