RPL4

Across TCGA cell cohorts, RPL4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPL4-associated genes across cancer lineages are AVP, OR3A2, and PRAMEF25. Each is linked with RPL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL4-to-partner and partner-to-RPL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by RPL4-low versus RPL4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL4→partner) and Y-score (partner→RPL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	2
BREAST	OR3A2 →	+1.249	+4.672	<.001	.002	3	1
BREAST	PRAMEF25 →	+0.061	+4.199	<.001	.007	3	1
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

AVP by RPL4 expression — BLOOD_Lymphoma

Explore this box plot interactively →