Across TCGA pan-cancer cohorts, RPL3P8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPL3P8’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL3P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL3P8 is over-expressed in tumor.
HNSC and THCA are the cancer types where RPL3P8 tumor–normal differential expression is most reproducible.