RPL3L

Across TCGA patient cohorts, RPL3L mutation is significantly associated with the RNA expression of many other genes, with 654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL3L-associated genes across cancer lineages are MIR507, ABHD5, and BAG2. Each is linked with RPL3L in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL3L-to-partner and partner-to-RPL3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR507 grouped by RPL3L-low versus RPL3L-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL3L→partner) and Y-score (partner→RPL3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	MIR507 →	+0.363	+7.939	<.001	.008	3	2
UCEC	ABHD5 →	+0.610	+3.513	.001	.002	3	2
UCEC	BAG2 →	+0.667	+3.459	.005	.005	3	2
UCEC	KIF1C →	+0.547	+2.638	<.001	.005	3	2
UCEC	RPA1 →	+0.585	+2.523	.001	.001	3	2
UCEC	HAUS2 →	+0.671	+2.595	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 654 associations by consensus.

MIR507 by RPL3L expression — PRAD

Explore this box plot interactively →