Across TCGA pan-cancer cohorts, RPL39P40 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RPL39P40’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPL39P40 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL39P40 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
COAD, KICH, and THCA are the cancer types where RPL39P40 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL39P40 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.