RPL38

Across TCGA patient cohorts, RPL38 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL38-associated genes across cancer lineages are A2ML1-AS2, OR14A16, and MIRLET7C. Each is linked with RPL38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL38-to-partner and partner-to-RPL38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A2ML1-AS2 grouped by RPL38-low versus RPL38-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL38→partner) and Y-score (partner→RPL38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	A2ML1-AS2 →	+0.128	+5.396	.001	.001	3	1
BRCA	OR14A16 →	+0.849	+4.649	<.001	.004	3	1
BRCA	MIRLET7C →	+0.780	+4.198	<.001	.009	3	1
BRCA	RN7SKP213 →	+0.154	+4.875	.004	.002	3	1
BRCA	CRIP1P3 →	+0.275	+5.044	<.001	.002	3	1
BRCA	RNMTL1P2 →	+0.067	+5.571	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

A2ML1-AS2 by RPL38 expression — BRCA

Explore this box plot interactively →