RPL38

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPL38 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RPL38-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and CD4+ naive T-cells. Each is linked with RPL38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL38-to-partner and partner-to-RPL38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by RPL38-low versus RPL38-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL38→partner) and Y-score (partner→RPL38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCD8+ T-cells →+0.089+6.142<.001.02731
COADCD8+ Tcm →+0.151+5.917<.001.03231
COADCD4+ naive T-cells →+0.047+6.142<.001.02731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ T-cells by RPL38 expression — COAD

Box plot of CD8+ T-cells in RPL38-low vs RPL38-high samples in COAD.

Explore this box plot interactively →

Exploration