RPL36AP51

Across TCGA pan-cancer cohorts, RPL36AP51 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPL36AP51 data layer compared with 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPL36AP51 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPL36AP51 expression acts as an unfavorable survival marker, although some lineages such as LUSC and MESO show a favorable association.

LUSC, LIHC, and HNSC are the cancer types where RPL36AP51 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Quartile	II,III,IV	0.579	0.310	.001	37	view →
LIHC	DFS	Tertile	All	0.343	0.570	.009	27	view →
HNSC	DFS	Tertile	All	0.181	0.437	.002	25	view →
MESO	DFS	Tertile	All	0.663	0.322	.017	24	view →
BRCA	DFS	Tertile	All	0.873	0.916	.009	19	view →
LUAD	OS	Quartile	II,III,IV	0.853	0.610	.008	17	view →
KIRC	DFS	Quartile	All	0.782	0.587	.002	14	view →
BLCA	OS	Tertile	IV	0.330	0.637	.016	13	view →
UCEC	DFS	Median	All	0.793	0.860	.022	12	view →
KIRP	OS	Quartile	All	0.516	0.845	.022	12	view →
UVM	OS	Median	All	0.765	1.000	.008	10	view →
SARC	DFS	Tertile	All	0.485	0.683	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RPL36AP51–LUSC (OS)

Open the LUSC breakdown →