RPL36AP21

Across TCGA pan-cancer cohorts, RPL36AP21 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPL36AP21 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RPL36AP21 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL36AP21 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

MESO, KIRC, and SKCM are the cancer types where RPL36AP21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.383	0.648	.005	47	view →
KIRC	DFS	Tertile	II,III,IV	0.817	0.535	.002	46	view →
SKCM	OS	Median	II,III,IV	0.895	0.789	<.001	45	view →
THCA	OS	Quartile	II,III,IV	1.000	0.300	.003	36	view →
COAD	DFS	Tertile	III,IV	0.789	0.466	.004	19	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	17	view →
LIHC	OS	Tertile	II,III,IV	0.695	0.223	<.001	16	view →
LUAD	OS	Quartile	II,III,IV	0.548	0.734	.035	10	view →
GBM	OS	Tertile	All	0.341	0.539	.003	9	view →
LUSC	DFS	Median	II,III,IV	0.655	0.506	.021	8	view →
BLCA	DFS	Median	III,IV	0.326	0.134	.018	5	view →
UVM	OS	Tertile	All	0.799	0.989	.029	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RPL36AP21–MESO (OS)

Open the MESO breakdown →