RPL36A

Across TCGA patient cohorts, RPL36A mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL36A-associated genes across cancer lineages are HNRNPH3P1, RNA5SP213, and RNA5SP36. Each is linked with RPL36A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL36A-to-partner and partner-to-RPL36A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPH3P1 grouped by RPL36A-low versus RPL36A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL36A→partner) and Y-score (partner→RPL36A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	HNRNPH3P1 →	+0.072	+5.010	<.001	.009	3	2
UCEC	RNA5SP213 →	+0.561	+3.123	<.001	.006	3	2
CESC	RNA5SP36 →	+0.374	+5.418	<.001	.005	3	1
CESC	RPLP1P10 →	+0.156	+5.669	<.001	.003	3	1
CESC	CCNJP1 →	+0.041	+5.669	<.001	.003	3	1
STAD	CDY2B →	+0.011	+4.798	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

HNRNPH3P1 by RPL36A expression — CESC

Explore this box plot interactively →