RPL36A

Across TCGA patient cohorts, RPL36A mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL36A-associated genes across cancer lineages are p70-S6K_pT389, PR, and Annexin-1. Each is linked with RPL36A in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL36A-to-partner and partner-to-RPL36A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p70-S6K_pT389 grouped by RPL36A-low versus RPL36A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL36A→partner) and Y-score (partner→RPL36A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p70-S6K_pT389 →	-0.215	-3.169	.015	.018	3	1
UCEC	PR →	+0.233	+2.999	.046	.035	3	1
UCEC	Annexin-1 →	+0.662	+3.189	.007	.010	3	1
UCEC	TFRC →	+0.527	+2.584	.033	.011	3	1
UCEC	Caspase-8 →	-0.295	-3.143	.011	.018	3	1
UCEC	CDK1_pY15 →	-0.230	-3.148	.022	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

p70-S6K_pT389 by RPL36A expression — UCEC

Explore this box plot interactively →