RPL36

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RPL36 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RPL36 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RPL36 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL36 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where RPL36 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.4750.274.0109view →
CCRCCOSMedianII,III,IV0.7250.935.0099view →
GBMOSQuartileAll0.6610.912.0302view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RPL36–PDAC (DFS)

Kaplan–Meier survival curve for RPL36 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration