Across TCGA pan-cancer cohorts, RPL35AP7 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPL35AP7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPL35AP7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPL35AP7 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, COAD, and THCA are the cancer types where RPL35AP7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPL35AP7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.074	.006	5	view →
COAD	All	All	+0.249	.008	4	view →
THCA	All	IV	−0.200	.033	3	view →
PRAD	All	All	+0.065	.013	2	view →
KIRC	All	II,III,IV	+0.036	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RPL35AP7 RNA expression & survival · all RPL35AP7 data types