RPL35AP6

Across TCGA pan-cancer cohorts, RPL35AP6 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPL35AP6 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RPL35AP6 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL35AP6 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

BRCA, ACC, and KICH are the cancer types where RPL35AP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	III,IV	0.583	0.366	.004	50	view →
ACC	DFS	Tertile	III,IV	0.074	0.499	.001	48	view →
KICH	OS	Tertile	II,III,IV	0.587	0.976	<.001	45	view →
STAD	DFS	Median	II,III,IV	0.475	0.591	.022	36	view →
LAML	DFS	Median	All	0.574	0.218	<.001	34	view →
UVM	OS	Tertile	III,IV	0.227	0.692	.034	30	view →
DLBC	OS	Tertile	III,IV	0.172	1.000	.014	28	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
SKCM	DFS	Tertile	IV	0.045	0.471	.016	15	view →
READ	OS	Tertile	IV	1.000	0.619	.031	12	view →
THYM	OS	Quartile	All	0.759	0.975	.020	6	view →
KIRC	DFS	Tertile	III,IV	0.758	0.545	.032	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPL35AP6–BRCA (DFS)

Open the BRCA breakdown →