Across TCGA pan-cancer cohorts, RPL35AP5 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL35AP5 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPL35AP5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPL35AP5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LIHC show a favorable association.
KIRC, THCA, and ACC are the cancer types where RPL35AP5 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.