RPL35AP35

Across TCGA pan-cancer cohorts, RPL35AP35 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RPL35AP35 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RPL35AP35 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL35AP35 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

CESC, SARC, and DLBC are the cancer types where RPL35AP35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	IV	0.230	0.688	.001	66	view →
SARC	OS	Tertile	All	0.718	0.854	.001	33	view →
DLBC	OS	Tertile	All	0.553	1.000	.004	27	view →
HNSC	OS	Tertile	IV	0.493	0.316	.024	21	view →
KIRP	DFS	Tertile	All	0.469	0.828	.006	20	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
COAD	DFS	Tertile	IV	0.264	0.568	.006	18	view →
UVM	DFS	Tertile	All	1.000	0.490	.041	12	view →
THYM	DFS	Tertile	All	1.000	0.577	.011	11	view →
LUSC	DFS	Quartile	II,III,IV	0.556	0.349	.016	8	view →
LUAD	DFS	Tertile	III,IV	0.641	0.442	.032	6	view →
ACC	DFS	Tertile	All	0.169	0.515	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RPL35AP35–CESC (OS)

Open the CESC breakdown →