RPL35AP28

Across TCGA pan-cancer cohorts, RPL35AP28 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RPL35AP28 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RPL35AP28 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RPL35AP28 expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

LUSC, BRCA, and LUAD are the cancer types where RPL35AP28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	All	0.820	0.642	<.001	74	view →
BRCA	DFS	Tertile	All	0.853	0.913	<.001	69	view →
LUAD	DFS	Tertile	III,IV	0.608	0.250	.013	39	view →
KIRP	DFS	Tertile	II,III,IV	0.856	0.461	.030	30	view →
ESCA	DFS	Quartile	All	1.000	0.233	.001	27	view →
UCEC	OS	Quartile	III,IV	0.921	0.810	.011	24	view →
LGG	OS	Tertile	All	0.949	0.861	.001	22	view →
KIRC	DFS	Tertile	IV	0.297	0.629	.023	18	view →
LIHC	DFS	Tertile	All	0.184	0.441	.030	18	view →
PAAD	DFS	Tertile	III,IV	0.275	0.794	.008	15	view →
CHOL	OS	Tertile	II,III,IV	1.000	0.417	.028	15	view →
CESC	DFS	Median	All	0.867	0.768	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RPL35AP28–LUSC (DFS)

Open the LUSC breakdown →