RPL35AP24

Across TCGA pan-cancer cohorts, RPL35AP24 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RPL35AP24 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPL35AP24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL35AP24 expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.

HNSC, UCS, and CESC are the cancer types where RPL35AP24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.118	0.426	.003	54	view →
UCS	OS	Tertile	All	0.639	0.266	.017	42	view →
CESC	OS	Tertile	IV	0.149	0.614	.002	36	view →
PAAD	OS	Tertile	All	0.284	0.612	<.001	36	view →
LUSC	DFS	Quartile	III,IV	0.120	0.897	<.001	21	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
MESO	OS	Tertile	IV	0.155	0.624	.004	18	view →
LUAD	OS	Tertile	III,IV	0.278	0.551	.014	18	view →
COAD	DFS	Tertile	III,IV	0.567	0.693	.035	15	view →
BLCA	DFS	Tertile	III,IV	0.335	0.512	.048	9	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	9	view →
GBM	OS	Tertile	All	0.235	0.439	.046	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RPL35AP24–HNSC (OS)

Open the HNSC breakdown →